Study at Charité Hospital Berlin confirms HeiQ Synbio helps reduce antibiotic resistance and healthcare associated infections

A recently published study1 conducted at Charité-Universitätsmedizin Hospital in Berlin confirms that cleaning with HeiQ Synbio cleaners create a surface microbiome that significantly reduces antimicrobial resistance genes related to healthcare associated infections.

Earlier studies in Belgian and Italian hospitals showed synbiotic cleaning to be a promising new technology for healthcare facilities (Caselli E, 2). A new study conducted at the renowned Charité-Universitätsmedizin Hospital in Berlin (Charité Berlin) investigated and compared the effects of different cleaning and disinfecting strategies on the surface microbiome in a clinical setting. Three surface treatments (Incidin Pro ECOLAB disinfectant, Brial Top ECOLAB cleaner, and HeiQ Synbio synbiotic cleaners) were applied subsequently in nine independent patient rooms at a neurological ward (Charité, Berlin). Weekly sampling of different surfaces demonstrated that synbiotic cleaning is a superior new method in hospital hygiene management and confirmed the prior findings from Caselli where HeiQ Synbio cleaners reduce antimicrobial resistance on hospital surfaces by up to 99.9%, reduce the incidence of healthcare associated infections by up to 52% and reduce healthcare associated infections related costs by up to 75%. These results are groundbreaking and induce a mindshift in hospital infection control strategies.

The full Charité Berlin study can be found here, and a detailed presentation will also be made at a seminar on May 11, 2022, at Interclean 2022 in Amsterdam, NL.

HeiQ responds to growing consumer interest in health, hygiene and safety with sustainable technology

Following its acquisition of Chrisal, a specialist biotech company with patented probiotic & synbiotic technology, HeiQ, the Swiss IP creator and established global brand in materials innovation, recently launched its new HeiQ Synbio cleaning range featured here. HeiQ Synbio uses synbiotics, the unique synthesis of pre- and probiotics towards sustainably improve microbiomes for people, pets and the environment.

A microbiologist himself and the original creator of the HeiQ Synbio technology, Dr. Robin Temmerman, CEO of HeiQ Chrisal, comments, “In their pursuit of perfect cleanliness, people have been using antibiotics, disinfectants and biocides for far too long and in excessive amounts, which can result in resistant microorganisms, so-called “super bugs”, that are a huge problem in hospitals. Our inspiration for the creation of synbiotic cleaning products at HeiQ Chrisal was founded in our conviction that synbiotics are the only true sustainable and effective solution to maintain outstanding cleanliness and reduce antimicrobial resistance. Synbiotic cleaners have been used for 10 years in hospitals contributing to decreasing infection rates. Today, more than 50 hospitals in Europe clean with HeiQ Synbio products.”

HeiQ Seminar on Synbiotic Cleaners and Healthcare Associated Infections at Interclean

HeiQ will be holding a Seminar highlighting the spectacular efficacy of synbiotic cleaning in healthcare facilities. A panel of experts will explain synbiotic cleaning – the technology, products and applications and present the results of the study conducted by Charité Berlin.

Registration: here

Speakers and topics:

  • Dr. Tilman Klassert, Jena University, “Evaluation of probiotic cleaning in Charité University Berlin”
  • Elad Amir, Design Cleaning Services Ltd, “Benefits of Synbio cleaning for facilities” and user cases
  • Dr. Robin Temmerman, HeiQ Chrisal, “Synbiotic hygiene – technology, products and applications”

Seminar: HeiQ Seminar – Beyond Clean – Revolutionary Synbiotic Cleaning for Healthcare Facilities
Date: 11th May 2022, from 14.30 till 16:30
Venue: Interclean, Amsterdam, NL, Rooms E104 & E 105, near the entrance of Hall 10
Registration: here


1 2022. Klassert TE et al., Comparative analysis of surface sanitization protocols on the bacterial community structures in the hospital environment, Clinical Microbiology and Infection,

2 Caselli, E. et al. Reducing healthcare-associated infections incidence by a probiotic-based sanitation system: A multicentre, prospective, intervention study. PLoS ONE 13, e0199616 (2018).

3 Tarricone, R., Rognoni, C., Arnoldo, L., Mazzacane, S. & Caselli, E. A Probiotic-Based Sanitation System for the Reduction of Healthcare Associated Infections and Antimicrobial Resistances: A Budget Impact Analysis. Pathogens 9, 502 (2020).

4 Caselli, E. et al. Impact of a probiotic-based hospital sanitation on antimicrobial resistance and HAI-associated antimicrobial consumption and costs: a multicenter study. Infect. Drug Resist. 12, 501–510 (2019).

5 Caselli, E. Hygiene: microbial strategies to reduce pathogens and drug resistance in clinical settings. Microb. Biotechnol. 10, 1079–1083 (2017).

6 Caselli, E. et al. Impact of a Probiotic-Based Cleaning Intervention on the Microbiota Ecosystem of the Hospital Surfaces: Focus on the Resistome Remodulation. PLOS ONE 11, e0148857 (2016).